| 768 | User Datagram ProtocolJ. Postel | Internet Standard | August 1980 |
| 793 | Transmission Control ProtocolJ. Postel · obsoleted by RFC 9293 | Internet Standard | September 1981 |
| 1191 | Path MTU discoveryJ. Mogul, S. Deering | Draft Standard | November 1990 |
| 2119 | Key words for use in RFCs to Indicate Requirement LevelsS. Bradner | Best Current Practice | March 1997 |
| 2522 | Photuris: Session-Key Management ProtocolP. Karn, W. Simpson | Experimental | March 1999 |
| 4303 | IP Encapsulating Security Payload (ESP)S. Kent | Proposed Standard | December 2005 |
| 4340 | Datagram Congestion Control Protocol (DCCP)E. Kohler, M. Handley, S. Floyd | Proposed Standard | March 2006 |
| 4346 | The Transport Layer Security (TLS) Protocol Version 1.1T. Dierks, E. Rescorla · obsoleted by RFC 5246 | Historic | April 2006 |
| 4347 | Datagram Transport Layer SecurityE. Rescorla, N. Modadugu · obsoleted by RFC 6347 | Historic | April 2006 |
| 4443 | Internet Control Message Protocol (ICMPv6) for the Internet Protocol Version 6 (IPv6) SpecificationA. Conta, S. Deering, M. Gupta, Ed. | Internet Standard | March 2006 |
| 4821 | Packetization Layer Path MTU DiscoveryM. Mathis, J. Heffner | Proposed Standard | March 2007 |
| 4960 | Stream Control Transmission ProtocolR. Stewart, Ed. · obsoleted by RFC 9260 | Proposed Standard | September 2007 |
| 5238 | Datagram Transport Layer Security (DTLS) over the Datagram Congestion Control Protocol (DCCP)T. Phelan | Proposed Standard | May 2008 |
| 5246 | The Transport Layer Security (TLS) Protocol Version 1.2T. Dierks, E. Rescorla · obsoleted by RFC 8446, RFC 9846 | Proposed Standard | August 2008 |
| 5763 | Framework for Establishing a Secure Real-time Transport Protocol (SRTP) Security Context Using Datagram Transport Layer Security (DTLS)J. Fischl, H. Tschofenig, E. Rescorla | Proposed Standard | May 2010 |
| 5764 | Datagram Transport Layer Security (DTLS) Extension to Establish Keys for the Secure Real-time Transport Protocol (SRTP)D. McGrew, E. Rescorla | Proposed Standard | May 2010 |
| 6066 | Transport Layer Security (TLS) Extensions: Extension DefinitionsD. Eastlake 3rd | Proposed Standard | January 2011 |
| 6298 | Computing TCP's Retransmission TimerV. Paxson, M. Allman, J. Chu, M. Sargent | Proposed Standard | June 2011 |
| 6347 | Datagram Transport Layer Security Version 1.2E. Rescorla, N. Modadugu · obsoleted by RFC 9147 | Proposed Standard | January 2012 |
| 7296 | Internet Key Exchange Protocol Version 2 (IKEv2)C. Kaufman, P. Hoffman, Y. Nir, P. Eronen, T. Kivinen | Internet Standard | October 2014 |
| 7525 | Recommendations for Secure Use of Transport Layer Security (TLS) and Datagram Transport Layer Security (DTLS)Y. Sheffer, R. Holz, P. Saint-Andre · obsoleted by RFC 9325 | Best Current Practice | May 2015 |
| 7841 | RFC Streams, Headers, and BoilerplatesJ. Halpern, Ed., L. Daigle, Ed., O. Kolkman, Ed. | Informational | May 2016 |
| 7924 | Transport Layer Security (TLS) Cached Information ExtensionS. Santesson, H. Tschofenig | Proposed Standard | July 2016 |
| 7983 | Multiplexing Scheme Updates for Secure Real-time Transport Protocol (SRTP) Extension for Datagram Transport Layer Security (DTLS)M. Petit-Huguenin, G. Salgueiro | Proposed Standard | September 2016 |
| 8174 | Ambiguity of Uppercase vs Lowercase in RFC 2119 Key WordsB. Leiba | Best Current Practice | May 2017 |
| 8201 | Path MTU Discovery for IP version 6J. McCann, S. Deering, J. Mogul, R. Hinden, Ed. | Internet Standard | July 2017 |
| 8439 | ChaCha20 and Poly1305 for IETF ProtocolsY. Nir, A. Langley | Informational | June 2018 |
| 8445 | Interactive Connectivity Establishment (ICE): A Protocol for Network Address Translator (NAT) TraversalA. Keranen, C. Holmberg, J. Rosenberg | Proposed Standard | July 2018 |
| 8446 | The Transport Layer Security (TLS) Protocol Version 1.3E. Rescorla · obsoleted by RFC 9846 | Proposed Standard | August 2018 |
| 8879 | TLS Certificate CompressionA. Ghedini, V. Vasiliev | Proposed Standard | December 2020 |
| 8996 | Deprecating TLS 1.0 and TLS 1.1K. Moriarty, S. Farrell | Best Current Practice | March 2021 |
| 9000 | QUIC: A UDP-Based Multiplexed and Secure TransportJ. Iyengar, Ed., M. Thomson, Ed. | Proposed Standard | May 2021 |
| 9002 | QUIC Loss Detection and Congestion ControlJ. Iyengar, Ed., I. Swett, Ed. | Proposed Standard | May 2021 |
| 9146 | Connection Identifier for DTLS 1.2E. Rescorla, Ed., H. Tschofenig, Ed., T. Fossati, A. Kraus | Proposed Standard | March 2022 |